5-HTP
(5-Hydroxy-L-Tryptophan)
The nutrient 5-Hydroxy-L-tryptophan
(5-HTP) is naturally extracted from Griffonia Simplicifolia, a tree that is native to the Ivory Coast and Ghana. 5-HTP is a precursor to the neurotransmitter Serotonin and can help to support a healthy neurotransmitter balance.
5-HTP is formulated into these Clarocet products:
Clarocet NRI, Clarocet ERT, Clarocet CS, Clarocet PM, Clarocet Junior

A Brief Introduction to 5-HTP

5-HTP is a derivative of the amino acid L-tryptophan, which is found in high-protein foods such as dairy products, fish, poultry and other lean meats. The supplement form of 5-HTP is naturally extracted from the seeds of Griffonia simplicifolia, a tree that is native to the Ivory Coast and Ghana.

Scientists have researched the emotional health benefits of 5-HTP in clinical and laboratory settings since the 1970s. 5-HTP is indicated for:

      • Depressed mood and mild to moderate mood changes caused by everyday stress
      • Occasional nervousness, nervous tension, and anxiety
      • Occasional sleep difficulty caused by restless

5-HTP is a nutrient that acts as a precursor to the neurotransmitter Serotonin and may help to support a healthy neurotransmitter balance following daily use for 2 to 6 weeks.

How 5-HTP is Thought to Work

5-Hydroxy-L-Tryptophan (5-HTP) is a precursor to Serotonin, the neurotransmitter that regulates mood, behavior, appetite, and sleep function. 5-HTP is produced naturally in the body when the amino acid L-tryptophan combines with vitamin C. In clinical trials, researchers have observed that approximately seventy percent of orally administered 5-HTP is absorbed directly into the blood stream. Unlike other dietary supplements, 5-HTP molecules are believed to be small enough to pass directly through the blood-brain barrier, thus increasing the availability of Serotonin in the Central Nervous System (CNS). Further analysis shows that 5-HTP administration also stimulates the activity of the neurochemicals Norepinephrine, Dopamine and Melatonin. It is thought that together, these mechanisms of action promote a healthy neurotransmitter balance in the brain and provide positive support for a depressed mood and mild to moderate mood swings caused by everyday stress, occasional nervousness, nervous tension and anxiety.

5-HTP Safety and Usage

5-HTP maintains an excellent safety profile when it is used as directed. A 35mg-200mg dose taken for two to six weeks is recommended to promote a healthy neurotransmitter balance. In certain instances, individuals may increase their daily intake of 5-HTP to up to 400mg to relieve a depressed mood and mild to moderate mood changes caused by everyday stress as well as occasional nervousness, nervous tension and anxiety.

What are the potential side effects of 5-HTP?

Side effects are rare and have been documented as mild to moderate in clinical study. They may include headache, gastrointestinal discomfort, and drowsiness. In the event that you experience an adverse reaction, discontinue use of this herb. 5-HTP does not cause withdrawal or discontinuation effects.

Does 5-HTP adversely interact with prescription drugs?

Taking 5-HTP in combination with prescription medications such as benzodiazepines, SSRIs, or SNRIs may cause drowsiness. If you are taking a prescription medication, it is recommended that you consult with your prescribing doctor before making any changes or additions to your current treatment plan.

What precautions should I take before beginning 5-HTP?

      • Consult with your healthcare provider before beginning a wellness plan that includes dietary supplements like 5-HTP
      • Do not take 5-HTP if you are pregnant or nursing
      • Do not take 5-HTP if you are currently taking a prescription MAOI
      • Do not take 5-HTP if you have Parkinson's disease and are taking Carbidopa
      • Children with Down's Syndrome should not take 5-HTP

Is 5-HTP safe for children?

5-HTP is generally well-tolerated when used by children between the ages of seven and thirteen. Because each child is unique, 5-HTP should be administered under the supervision of a professional healthcare provider.

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